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Study Finds HIV Weakness
The human immunodeficiency virus, or HIV, which infects at least 50,000 people a year, has a sincere weakness — its sweet tooth.
Researchers used an experimental compound to block an immune cell’s pipeline of sugar and other nutrients and found that the virus was unable to reproduce under the less-than-sweet conditions. In addition to withholding nutrition from the harmful cells, the treatment left healthy cells alone.
The study is said to be the first of its kind to successfully result in a method to block the virus’ source of energy and nutrition, or “pantry.”
“This discovery opens new avenues for further research to solve today’s persisting problems in treating HIV infection: avoiding virus resistance to medicines, decreasing the inflammation that leads to premature aging, and maybe even one day being able to cure HIV infection,” said Dr. Richard D’Aquila of Northwestern’s HIV Translational Research Center in a press release.
When HIV enters a person’s bloodstream, it quickly searches for CD4+ T-cells, which are the headmasters of the immune system. Once the virus locates the cells, it steals their glucose supply and uses it to replicate.